International peer-reviewed publications
(blue publications focus on the brainstem / blue spot)
2024
Klinger HM, Healy BC, Hanseeuw BJ, Jones RN, Boyle R, Townsend DL, Properzi MJ, Coughlan GT, Seto M, Birkenbihl C, Farrell ME, Papp KV, Chhatwal JP, Yang HS, Schultz AP, Amariglio RE, Jacobs HIL, Price JC, Johnson KA, Rentz DM, Sperling RA, Buckley RF (2024) Latent change-on-change between amyloid accumulation and cognitive decline. Alzheimer's & Dementia, accepted (IF 13.1)
Lam AD, Thibault EG, Mayblyum DV, Hsieh S, Pellerin KR, Sternberg EJ, Viswanathan A, Buss S, Sarkis RA, Jacobs HIL, Johnson KA, Sperling RA (2024) Association of seizure foci and location of tau and amyloid deposition and brain atrophy in patients with Alzheimer's disease and seizures. Neurology, 103(9), e209920 (IF 8.0)
Engels-Domínguez N, Riphagen JM, Van Egroo M, Koops EA, Smegal L, Becker JA, Prokopiou PC, Bueicheku E, Kwong K, Rentz DM, Salat DH, Sperling RA, Johnson KA, Jacobs HIL (2024). Lower locus coeruleus integrity signals elevated entorhinal tau and clinical progression in asymptomatic older individuals. Annals of Neurology, 96(4), 650-661 (IF 8.1)
Beckers E, Van Egroo M, Ashton NJ, Blennow K, Vandewalle G, Zetterberg H, Poser BA, Jacobs HIL (2024) Microstructural associations between locus coeruleus, cortical and subcortical regions are modulated by astrocyte reactivity: a 7T MRI adult lifespan study. Cerebral Cortex, 34(6), bhae261 (IF 2.9)
Boyle R, Townsend DL, Klinger HM, Scanlon CE, Yuan Z, Coughlan GT, Seto M, Shirzadi Z, Yau WY, Jutten RJ, Schneider C, Farrell ME, Hanseeuw BJ, Mormino EC, Yang HS, Papp KV, Amariglio RE, Jacobs HIL, Price JC, Chhatwal JP, Schultz AP, Properzi MJ, Rentz DM, Johnson KA, Sperling RA, Hohman TJ, Donohue MC, Buckley RF (2024). Identifying longitudinal cognitive resilience from cross-sectional amyloid, tau and neurodegeneration. Alzheimer Research and Therapy, 16(1), 148 (IF 8.0)
Pahl J, Prokopiou PC, Bueicheku E, Schultz AP, Papp KV, Farrell ME, Rentz DM, Sperling RA, Johnson KA, Jacobs HIL (2024). Locus coeruleus integrity and left frontoparietal connectivity provide resilience against attentional decline in preclinical Alzheimer's disease. Alzheimer Research and Therapy, 16(1), 119 (IF 8.0)
Engels-Domínguez N, Koops EA, Hsieh S, Wiklund EE, Schultz AP, Riphagen JM, Prokopiou PC, Hanseeuw BJ, Rentz DM, Sperling RA, Johnson KA, Jacobs HIL (2024). Lower in vivo locus coeruleus integrity is associated with lower cortical thickness in older individuals with elevated Alzheimer's disease pathology: a cohort study. Alzheimer Research and Therapy, 16(1), 129 (IF 8.0).
Farrell ME, Thibault EG, Becker JA, Price JC, Healy BC, Hanseeuw BJ, Buckley RF, Jacobs HIL, Schultz AP, Chen CD, Sperling RA, Johnson KA (2024). Spatial extent as a sensitive amyloid-PET metric in preclinical Alzheimer's disease. Alzheimer's & Dementia, 20(8), 5434-5449 (IF 13.1)
Beckers E, Riphagen JM, Van Egroo M, Bennett DA, Jacobs HIL (2024). Sparse asymmetry in locus coeruleus pathology in Alzheimer's disease. Journal of Alzheimer's disease, 99(1), 105-111 (IF 3.4)
Diez I, Ortiz-Teran L, Ng T, Albers MW, Marshall G, Orwig W, Kim CM, Bueicheku E, Montal V, Olofsson J, Vannini P, El Fakhri G, Sperling R, Johnson KA, Jacobs HIL, Sepulcre J (2024). Tau propagation in the brain olfactory circuits contributes to smell perception changes in aging. Nature Communications, 15(1), 4809 (IF 14.7)
Lee S, Zide BS, Palm ST, Drew WJ, Sperling RA, Jacobs HIL, Siddiqi SH, Donovan NJ (2024). Specific associations of worry with amyloid-beta but not tua in cognitively unimpaired older adults. American Journal of Geriatric Psychiatry, S1064-7481(24)00327-0 (IF 4.4)
Schneider C, Prokopiou PC, Papp KV, Engels-Domînguez N, Hsieh S, Juneau TA, Schultz AP, Rentz DM, Sperling RA, Johnson KA, Jacobs HIL (2024). Atrophy links lower novelty-related locus coeruleus connectivity to cognitive decline in preclinical Alzheimer's disease. Alzheimer's & Dementia, 20(6), 3958-3971. (IF 13.1)
Bueichekü E, Diez I, Kim CM, Becker JA, Koops EA, Kwong K, Papp KV, Salat DH, Bennett DH, Rentz DM, Sperling RA, Johnson KA, Sepulcre J, Jacobs HIL (2024). Spatiotemporal patterns of locus coeruleus integrity predict cortical tau and cognition. Nature Aging, 4(5), 625-637 (IF 17.0)
Beckers E, Riphagen JM, Van Egroo M, Bennett DA, Jacobs HIL (2024). Sparse asymmetry in locus coeruleus pathology in Alzheimer's disease. Journal of Alzheimer's disease, 99(1), 105-111 (IF 3.4)
Van Egroo M, van Someren EJW, Grinberg LT, Bennett DA,, Jacobs HIL (2024). Associations of 24-hour rest-activity rhythm fragmentation, cognitive decline, and postmortem locus coeruleus hypopigmentation in Alzheimer's Disease. Annals of Neurology, 95(4), 653-664 (IF 8.1)
Zide BS, Donovan NJ, Lee S, Nag S, Bennett DA, Jacobs HIL (2024). Social activity mediates locus coeruleus tangle-related cognition in older adults. Molecular Psychiatry, 29(7), 2001-2008 (IF 9.6)
Lam AD, Thibault EG, Mayblyum DV, Hsieh S, Pellerin KR, Sternberg EJ, Viswanathan A, Buss S, Sarkis RA, Jacobs HIL, Johnson KA, Sperling RA (2024) Association of seizure foci and location of tau and amyloid deposition and brain atrophy in patients with Alzheimer's disease and seizures. Neurology, 103(9), e209920 (IF 8.0)
Engels-Domínguez N, Riphagen JM, Van Egroo M, Koops EA, Smegal L, Becker JA, Prokopiou PC, Bueicheku E, Kwong K, Rentz DM, Salat DH, Sperling RA, Johnson KA, Jacobs HIL (2024). Lower locus coeruleus integrity signals elevated entorhinal tau and clinical progression in asymptomatic older individuals. Annals of Neurology, 96(4), 650-661 (IF 8.1)
Beckers E, Van Egroo M, Ashton NJ, Blennow K, Vandewalle G, Zetterberg H, Poser BA, Jacobs HIL (2024) Microstructural associations between locus coeruleus, cortical and subcortical regions are modulated by astrocyte reactivity: a 7T MRI adult lifespan study. Cerebral Cortex, 34(6), bhae261 (IF 2.9)
Boyle R, Townsend DL, Klinger HM, Scanlon CE, Yuan Z, Coughlan GT, Seto M, Shirzadi Z, Yau WY, Jutten RJ, Schneider C, Farrell ME, Hanseeuw BJ, Mormino EC, Yang HS, Papp KV, Amariglio RE, Jacobs HIL, Price JC, Chhatwal JP, Schultz AP, Properzi MJ, Rentz DM, Johnson KA, Sperling RA, Hohman TJ, Donohue MC, Buckley RF (2024). Identifying longitudinal cognitive resilience from cross-sectional amyloid, tau and neurodegeneration. Alzheimer Research and Therapy, 16(1), 148 (IF 8.0)
Pahl J, Prokopiou PC, Bueicheku E, Schultz AP, Papp KV, Farrell ME, Rentz DM, Sperling RA, Johnson KA, Jacobs HIL (2024). Locus coeruleus integrity and left frontoparietal connectivity provide resilience against attentional decline in preclinical Alzheimer's disease. Alzheimer Research and Therapy, 16(1), 119 (IF 8.0)
Engels-Domínguez N, Koops EA, Hsieh S, Wiklund EE, Schultz AP, Riphagen JM, Prokopiou PC, Hanseeuw BJ, Rentz DM, Sperling RA, Johnson KA, Jacobs HIL (2024). Lower in vivo locus coeruleus integrity is associated with lower cortical thickness in older individuals with elevated Alzheimer's disease pathology: a cohort study. Alzheimer Research and Therapy, 16(1), 129 (IF 8.0).
Farrell ME, Thibault EG, Becker JA, Price JC, Healy BC, Hanseeuw BJ, Buckley RF, Jacobs HIL, Schultz AP, Chen CD, Sperling RA, Johnson KA (2024). Spatial extent as a sensitive amyloid-PET metric in preclinical Alzheimer's disease. Alzheimer's & Dementia, 20(8), 5434-5449 (IF 13.1)
Beckers E, Riphagen JM, Van Egroo M, Bennett DA, Jacobs HIL (2024). Sparse asymmetry in locus coeruleus pathology in Alzheimer's disease. Journal of Alzheimer's disease, 99(1), 105-111 (IF 3.4)
Diez I, Ortiz-Teran L, Ng T, Albers MW, Marshall G, Orwig W, Kim CM, Bueicheku E, Montal V, Olofsson J, Vannini P, El Fakhri G, Sperling R, Johnson KA, Jacobs HIL, Sepulcre J (2024). Tau propagation in the brain olfactory circuits contributes to smell perception changes in aging. Nature Communications, 15(1), 4809 (IF 14.7)
Lee S, Zide BS, Palm ST, Drew WJ, Sperling RA, Jacobs HIL, Siddiqi SH, Donovan NJ (2024). Specific associations of worry with amyloid-beta but not tua in cognitively unimpaired older adults. American Journal of Geriatric Psychiatry, S1064-7481(24)00327-0 (IF 4.4)
Schneider C, Prokopiou PC, Papp KV, Engels-Domînguez N, Hsieh S, Juneau TA, Schultz AP, Rentz DM, Sperling RA, Johnson KA, Jacobs HIL (2024). Atrophy links lower novelty-related locus coeruleus connectivity to cognitive decline in preclinical Alzheimer's disease. Alzheimer's & Dementia, 20(6), 3958-3971. (IF 13.1)
Bueichekü E, Diez I, Kim CM, Becker JA, Koops EA, Kwong K, Papp KV, Salat DH, Bennett DH, Rentz DM, Sperling RA, Johnson KA, Sepulcre J, Jacobs HIL (2024). Spatiotemporal patterns of locus coeruleus integrity predict cortical tau and cognition. Nature Aging, 4(5), 625-637 (IF 17.0)
Beckers E, Riphagen JM, Van Egroo M, Bennett DA, Jacobs HIL (2024). Sparse asymmetry in locus coeruleus pathology in Alzheimer's disease. Journal of Alzheimer's disease, 99(1), 105-111 (IF 3.4)
Van Egroo M, van Someren EJW, Grinberg LT, Bennett DA,, Jacobs HIL (2024). Associations of 24-hour rest-activity rhythm fragmentation, cognitive decline, and postmortem locus coeruleus hypopigmentation in Alzheimer's Disease. Annals of Neurology, 95(4), 653-664 (IF 8.1)
Zide BS, Donovan NJ, Lee S, Nag S, Bennett DA, Jacobs HIL (2024). Social activity mediates locus coeruleus tangle-related cognition in older adults. Molecular Psychiatry, 29(7), 2001-2008 (IF 9.6)
2023
Hanseeuw BJ, Jacobs HIL, Schultz AP, Buckley RF, Farrell ME, Guehl NJ, Becker JA, Properzi M, Sanchez JS, Quiroz YT, Vannini P, Sepulcre J, Yang HS, Chhatwal JP, Gatchel J, Marshall GA, Amariglio R, Papp K, Rentz DM, Normandin M, Price JC, Healy BC, El Fakhri G, Sperling RA, Johnson KA (2023). Association of pathological and volumetric biomarker changes with cognitive decline in clinically normal adults: Harvard Aging Brain Study. Neurology, 101(24), e2533-e2544 (IF 8.4)
Beckers E, Campbell I, Sharifpour R, Paparella I, Berger A, Aizpura JFB, Koshmanova E, Mortazavi N, Talwar P, Sherif S, Jacobs HIL, Vandewalle G (2023). Impact of repeated short light exposures on sustained pupil responses in an fMRI environment. Journal of Sleep Research, 33(4), e14085 (IF 3.4)
Scott MR, Edwards NC, Properzi MJ, Jacobs HIL, Price JC, Lois C, Farrell ME, Hanseeuw BJ, Thibault EG, Rentz DM, Johnson KA, Sperling RA, Schultz AP, Buckley RF (2023). Contribution of extra cerebral tracer retention and partial volume effects to sex differences in Flortaucipir-PET signal. Journal of Cerebral Blood Flow and Metabolism, 44(1), 131-141 (IF 4.9)
Wolters AF, Heijmans M, Priovoulos N, Jacobs HIL, Postma AA, Temel Y, Kuijf ML, Michielse S (2023). Neuromelanin related ultra-high field signal intensity of the locus coeruleus differs between Parkinson's disease and controls. Neuroimage Clinical, 39, 103479 (IF 3.4)
Berger A, Koshmanova E, Beckers E, Sharifpour R, Paparella I, Campbell I, Mortazavi N, Balda F, Yi YJ, Lamalle L, Dricot L, Phillips C, Jacobs HIL, Talwar P, El Tahry R, Sherif S, Vandewalle G (2023). Structural and functional characterisation of the locus coeruleus in young and late-middle aged individuals. Frontiers in Neuroimaging, 21(2), 1207844
Prokopiou PC, Engels-Domínguez N, Schultz AP, Sepulcre J, Koops EA, Papp KV, Marshall GA, Normandin MD, El Fakhri G, Rentz D, Sperling RA, Johnson KA, Jacobs HIL (2023). Association of novelty-related locus coeruleus function with entorhinal tau deposition and memory decline in preclinical Alzheimer's disease. Neurology, 101(12), e1206-1217 (IF 8.4)
Arleo A, Bares M, Bernard JA, Bogoian HR, Bruchhage MMK, Bryant P, Carlson ES, Chan CCH, Chen LK, Chung CP, Dotson VM, Filip P, Guell X, Habas C, Jacobs HIL, Kakei S, Lee TMC, Leggio M, Misiura M, Mitoma H, Olivito G, Ramanoël S, Rezaee Z, Samstag CL, Schmahmann JD, Sekiyama K, Wong CHY, Yamashita M, Manto M (2023). Consensus Paper: Cerebellum and Aging. Cerebellum, 23(2), 802-832 (IF 2.7)
Veréb D, Mijalkov M, Canal-Garcia A, Chang YW, Gomez-Ruis E, Gerboles BZ, Kivipelto M, Svenningsson P, Zetterberg H, Volpe G, Betts MJ, Jacobs H, Pereira JB (2023). Age-related differences in the functional topography of the locus coeruleus and their implications for cognitive and affective functions. eLife, 12:RP87188 (IF 6.4)
Drowse J, Ohndorf A, Richter N, Bischof GN, Fassbender R, Behfar Q, Gramespacher H, Dillen K, Jacobs HIL, Kukolja J, Fink GR, Onur OA (2023). Serum cortisol is negatively related to hippocampal volume, brain structure and memory performance in healthy aging and Alzheimer's disease. Frontiers Aging Neuroscience, 15: 1154112 (IF 4.1)
Freeze WM, Van Veluw SJ, Jansen WJ, Bennett DA, Jacobs HIL. (2023). Locus coeruleus pathology is associated with cerebral microangiopathy at autopsy. Alzheimer's & Dementia, 19(11), 5023-5035 (IF 13.1).
Van Egroo M, Riphagen JM, Ashton NJ, Janelidze S, Sperling RA, Johnson KA, Yang HS, Bennett DA, Blennow K, Hansson O, Zetterberg H, Jacobs HIL (2023). Ultra-high field imaging, plasma markers and autopsy data uncover a specific rostral locus coeruleus vulnerability to hyperphosphorylated tau. Molecular Psychiatry, 28(6), 2412-2422 (IF 9.6)
Koshmanova E, Berger A, Beckers E, Campbell I, Mortazavi N, Sharifpour R, Paparella I, Balda F, Berthomier C, Degueldre C, Salmon E, Lamalle L, Bastin C, Van Egroo M, Philips C, Maquet P, Collette F, Muto V, Chylinski D, Jacobs HIL, Talwar P, Sherif S, Vandewalle G. (2023). Locus coeruleus activity while awake is associated with REM sleep quality in older individuals. JCI Insight, e172008 (IF 6.3)
Ehrenberg AJ, Kelberman MA, Liu KY, Dahl MJ, Weinshenker D, Falgas N, Dutt S, Mather M, Betts MJ, Winer JR, Teipel S, Weigand AJ, Eschenko O, Hämmerer D, Leiman M, Counts SE, Shine JM, Robertson I, Levey AI, Lancini E, Ludwig M, Son G, Schneider C, Van Egroo M, Liguori C, Qang Q, Vazey EM, Rodrigeuz-Procel F, Haag L, Bondi M, Vanneste S, Freeze WM, Yi YJ, Maldinov M, Gatchel J, Satpati A, Babiloni C, Kremen WS, Howard R, Jacobs HIL*, Grinberg LT* (2023). Priorities for research on neuromodulatory subcortical systems in Alzheimer’s disease: position paper from the NSS PIA of ISTAART. Alzheimer’s & Dementia, 19(5), 2182-2196 (IF 13.1)
Engels-Dominguez N*, Koops EA*, Prokopiou PC, Van Egroo M, Schneider C, Riphagen JM, Singhal T, Jacobs HIL (2023) State-of-the-art imaging of neuromodulatory subcortical systems in aging and Alzheimer's disease: challenges and opportunities. Neuroscience and Biobehavioral Reviews, 144, 104998 (IF 7.6)
2022
Koops EA, Jacobs HIL (2022). Untangling white matter fibre changes in Alzheimer's disease and small vessel disease. Brain, 146(2), 413-415 (IF 11.9).
Drenthen GS, Backes WH, Freeze WM, Jacobs HIL, Verheggen ICM, van Boxtel MPJ, Hoff EI, Verhey FR, Jansen JFA (2022). Rich-club connectivity of the structural covariance network relates to memory processes in mild cognitive impairment and Alzheimer's disease. Journal of Alzheimer's disease, 89(1), 209-217 (IF 3.4)
Riphagen JM, Van Hooren RWE, Kenis G, Verhey FRJ, Jacobs HIL (2022) Distinct patterns link the BDNF Val66Met polymorphism to Alzheimer pathologies. Journal of Alzheimer's disease, 88(2), 447-453 (IF 3.4)
Buckley RF, O'Donnell A, McGrath ER, Jacobs HIL, Lois C, Satizabal CL, Ghosh S, Rubinstein ZB, Murabito JM, Sperling RA, Johnson KA, Seshadri S, Beiser AS (2022). Menopause status moderates sex differences in tau burden: a Framingham PET study. Annals of Neurology, 92(1), 11-22 (IF 8.1)
Farrell ME, Papp KV, Buckley RF, Jacobs HIL, Schultz AP, Properzi MJ, Vannini P, Hanseeuw BJ, Rentz DM, Johnson KA, Sperling RA (2022). Association of emerging β-Amyloid and tau pathology with early cognitive changes in clinically normal older adults. Neurology, 98(15), e1512-e1524. (IF 8.4)
Pagen LHG, Poser BA, van Boxtel MPJ, Priovoulos N, van Hooren RWE, Verhey FRJ, Jacobs HIL (2022) Worry modifies the relationship between locus coeruleus activity and emotional mnemonic discrimination. Brain Sciences, 12(3), 381 (IF 2.7)
Prokopiou PC, Engels-Dominguez N, Papp KV, Scott MR, Schultz AP, Schneider C, Farrell ME, Buckley RF, Quiroz YT, El Fakhri G, Rentz DM, Sperling RA, Johnson KA, Jacobs HIL (2022) Lower novelty-related locus coeruleus function is associated with Aβ-related cognitive decline in clinically healthy individuals. Nature Communications, 13(1), 1571 (IF 14.7)
Jacobs HIL, Becker JA, Kwong K, Munera D, Ramirez-Gomez L, Engels-Dominguez N, Sanchez JS, Vila-Castelar C, Baena A, Sperling RA, Johnson KA, Lopera F, Quiroz Y (2022). Waning locus coeruleus integrity precedes cortical tau accrual in preclinical autosomal dominant Alzheimer's disease. Alzheimer's & Dementia, 19(1), 169-180 (IF 13.1)
Jacobs HIL, O'Donnell A, Satizabal CL, Lois C, Kojis D, Hanseeuw B, Thibault E, Sanchez JS, Buckley RF, Yang Q, DeCarli C, Killiany R, Sargurupremraj M, Sperling RA, Johnson KA, Beiser AS, Seshadri S (2022). Associations between brainstem volume and Alzheimer's disease pathology in middle-aged individuals of the Framingham Heart Study. Journal of Alzheimer's disease, 86(4), 1603-1609 (IF 3.4)
Van Egroo M, Koshmanova E, Vandewalle G, Jacobs HIL (2022). Importance of the locus coeruleus-norepinephrine system in sleep-wake regulation: implications for aging and Alzheimer's disease. Sleep Medicine Reviews, 62, 101592 (IF 11.2)
Terneusen A, Winkens I, van Heugten C, Start S, Jacobs HIL, Ponds R, Quaedflieg C (2022). Neural correlates of impaired self-awareness of deficits after acquired brain injury: a systematic review. Neuropsychology Review, 33(1), 222-237 (IF 5.4)
2021
Becker AB, van Oudenhove L, Weerts ZZRM, Jacobs HIL, Priovoulos N, Poser BA, Ivanov D, Gholamrezaei A, Aziz Q, Eisenbruch S, Masche AAM, Keszthelyi D (2021). Evidence for engagement of the nucleus of the solitary tract in processing intestinal chemonociceptive input irrespective of conscious pain response in healthy humans. Pain, 163(8), 1520-1529 (IF 5.9)
Van Egroo M, van Hooren RWE, Jacobs HIL (2021). Associations between locus coeruleus integrity and nocturnal awakenings in the context of Alzheimer's disease plasma biomarkers: a 7T MRI study. Alzheimer's Research & Therapy, 13(1), 159 (IF 8.0)
Jacobs HIL, Becker JA, Kwong K, Engels-Dominguez N, Prokopiou PC, Papp KV, Properzi M, Hampton OL, d’Oleire Uquillas F, Sanchez JS, Rentz DM, El Fakhri G, Normandin MD, Price JC, Bennett DA, Sperling RA, Johnson KA (2021) In vivo and neuropathology data support locus coeruleus integrity as indicator of Alzheimer's disease pathology and cognitive decline. Science Translational Medicine, 13(6), eabj2511 (IF 15.8), [LINK TO PUBLICATION]
Fox-Fuller JT, Torrico-Teave H, d'Oleire Uquillas F, Chen K, Su Y, Chen Y, Brickhouse M, Sanchez JS, Aguero C, Jacobs HIL, Hampton O, Guzman-Velez E, Vila-Castelar C, Aguirre-Acevedo DC, Baena A, Artola A, Martinez J, Pluim CF, Alvarez S, Ochoa-Escudero M, Reiman EM, Sperling RA, Lopera F, Johnson KA, Dickerson BC, Quiroz YT (2021). Cortical thickness across the lifespan in a Colombian cohort with autosomal-dominant Alzheimer's disease: a cross-sectional study. Alzheimer's & Dementia: diagnosis, assessment and disease monitoring, 13(1), e12233 (IF 4.0).
van der Thiel MM, Freeze WM, Verheggen ICM, Wong SM, de Jong JJA, Postma AA, Hoff EI, Gronenschild EHBM, Verhey FR, Jacobs HIL, Ramakers IHGB, Backes WH, Jansen JFA (2021). Associations of increased interstitial fluid with vascular and neurodegenerative abnormalities in a memory clinic sample. Neurobiology of Aging, 106, 257-267 (IF 3.7)
Chen X, Onur OA, Richter N, Fassbender R, Gramespacher H, Behfar Q, Reutern B, Dillen KN, Jacobs HIL, Kukolja J, Fink GR, Dronse J (2021). Concordance of intrinsic brain connectivity measures is disrupted in Alzheimer's disease. Brain Connectivity, 13(6), 344-355 (IF 2.4)
Nellessen N, Onur OA, Richter N, Jacobs HIL, Dillen KNH, Reutern BV, Langen KJ, Fink GR, Kukolja J (2021). Differential neural structures, intrinsic functional connectivity, and episodic memory in subjective cognitive decline and healthy controls. Neurobiology of Aging, 105, 159-173 (IF 3.7)
Jacobs H, Schoemaker D, Torrico-Teave H, Zuluaga Y, Velilla-Jimenez L, Ospina-Villegas C, Lopera F, Arboleda-Velasquez J, Quiroz YT (2021) Specific abnormalities in white matter pathways as interface to small vessel disease and cognition in CADASIL individuals. Brain Connectivity, 12(1), 52-60 (IF 2.4)
Yang F, Chowdhury SR, Jacobs HIL, Sepulcre J, Wedeen VJ, Johnson KA, Dutta J. (2021) Longitudinal predictive modeling of tau progression along the structural connectome. Neuroimage,237, 118126 (IF 4.7)
Mayblyum DV, Becker JA, Jacobs HIL, Buckley RF, Schultz AP, Sepulcre J, Sanchez JS, Rubinstein ZB, Katz SR, Moody KA, Vannini P, Papp KV, Rentz DM, Price JC, Sperling RA, Johnson KA, Hanseeuw BJ (2021) Comparing PET and MRI biomarkers predicting cognitive decline in preclinical Alzheimer's disease. Neurology, 96(24), e2933-43 (IF 8.4)
Farmer AD, Strzelczyk A. Finisguerra A, Gourine AV, Gharabaghi A, Hasan A, Burger AM, Jaramillo AM, Mertens A, Majid A, Verkuil B, Badran BW, Ventura-Bort C, Gaul C, Beste C, Warren CM, Quintana DS, Hämmerer D, Elena Freri E, Frangos E, Tobaldini E, Kaniusas E, Capone F, Rosenow F, Panetsos F, Ackland G, Kaithwas G, O’Leary GH, Genheimer H, Jacobs HIL, Van Diest I, Schoenen J, Redgrave J, Fang J, Deuchars J, Széles JC, Thayer JF, More K, Vonck K, Steenbergen L, Vianna LC, McTeague L, Ludwig M, Veldhuizen MG, De Couck M, Casazza M, Keute M, Bikson M, Andreatta M, D’Agostini M, Weymar M, Betts M, Prigge M, Kaess M, Roden M, Thai M, Schuster NM, Montano N, Hansen N, Kroemer NB, Rong P, Fischer R, Howland RH, Sclocco R, Sellaro R, Garcia RG, Bauer S, Gancheva S, Stavrakis S, Kampusch S, Deuchars SA, Wehner S, Laborde S, Usichenko T, Polak T, Zaehle T, Borges U, Teckentrup V, Jandackova VK, Napadow V, Koenig J. (2021) International consensus based review and recommendations for minimum reporting standards in research on transcutaneous vagus nerve stimulation. Frontiers in Human Neuroscience, Brain Imaging and Stimulation, 14, 568051 (IF 2.4)
Pagen LHG, Smeets T, Schmiedek L, Yassa MA, Verhey FRJ, Jacobs HIL (2021) Elevated activity of the sympathetic nervous system is related to diminished practice effects in memory: a pilot study. Journal of Alzheimer's disease, 80(4), 1675-1685 (IF 3.4)
van Hooren RWE, Verhey FRJ, Ramakers IHGB, Jansen WJ, Jacobs HIL (2021). Elevated norepinephrine metabolism is linked to cortical thickness in the context of Alzheimer's disease pathology, Neurobiology of Aging, 102, 17-22 (IF 3.7)
Riphagen JM, Van Egroo M, Jacobs HIL (2021) Elevated norepinephrine metabolism gauges Alzheimer's disease-related pathology and memory decline. Journal of Alzheimer's disease, 102,17-22 (IF 3.4)
Jacobs HIL, Riphagen JM, Ramakers IHGB, Verhey FRJ. (2021). Alzheimer's disease pathology: pathways between central norepinephrine activity, memory and neuropsychiatric symptoms. Molecular Psychiatry. 26(3), 897-906 (IF 9.6)
Sanchez JS, Becker JA, Jacobs HIL, Hanseeuw BJ, Jiang S, Schultz AP, Properzi MJ, Katz SR, Beiser A, Satizabal CL, O'Donnell A, DeCarli C, Killiany R, El Fakhri G, Normandin MD, Gomez-Isla T, Quiroz YT, Rentz DM, Sperling RA, Seshadri S, Augustinack J, Price JC, Johnson KA (2021) The cortical origin and initial spread of medial temporal tauopathy in Alzheimer's disease assessed with positron emission tomography. Science Translational Medicine, 13(577), eabc0655 (IF 15.8)
Sanchez JS, Hanseeuw BJ, Lopera F, Sperling RA, Baena A, Bocanegra Y, Aguilon D, Guzman-Velez E, Pardilla-Delgado E, Ramirez-Gomez L, Vila-Castelar C, Martinez JE, Fox-Fuller JT, Ramos C, Ochoa-Escudero M, Alvarez S, Jacobs HIL, Schultz AP, Gatchel JR, Becker JA, Katz SR, Mayblyum DV, Price JC, Reiman EM, Johnson KA, Quiroz YT (2021) Longitudinal amyloid and tau accumulation in autosomal dominant Alzheimer's disease: findings from the Colombia-Boston (COLBOS) biomarker study. Alzheimer Research & Therapy, 13(1), 27 (IF 8.0)
2020
Rienäcker F, Van Gerven PWM, Jacobs HIL, Eck J, van Heugten CM, Guerreiro MJS (2020) The neural correlates of visual and auditory cross-modal selective attention in aging. Frontiers in Aging Neuroscience, 12, 498978 (IF 4.1)
Song TA, Chowdhury SR, Yang F, Jacobs HIL, Sepulcre J, Wedeen VJ, Johnson KA, Dutta J (2020) A physics-informed geometric learning model for pathological tau spread in Alzheimer's disease. Med Image Comput Comput Assist Interv, 12267, 418-427.
Farrell ME, Jiang S, Schultz AP, Properzi MJ, Price JC, Becker JA, Jacobs HIL, Hanseeuw BJ, Rentz DM, Villemagne VL, Papp KV, Mormino EC, Betensky RA, Johnson KA, Sperling RA, Buckley RF (2020) Defining the lowest threshold for amyloid-PET to predict future cognitive decline and amyloid accumulation. Neurology, 96(4), e619-e631 (IF 8.4).
Priovoulos N*, van Boxel SCJ*, Jacobs HIL, Poser BA, Uludag K, Verhey FRJ, Ivanov D (2020) Unraveling the contributions to the neuromelanin-MRI contrast. Brain Structure and Function, 225(9), 2757-2274, (IF 2.7)
Freeze WM, van der Thiel M, de Bresser J, Klijn CJM, van Etten ES, Jansen JFA, van der Weerd L, Jacobs HIL, Backes WH, van Veluw SJ (2020) CSF Enhancement on post-contrast fluid-attenuated inversion recovery images: a systematic review. Neuroimage Clinical, 28: 102456 (IF 3.4)
Hampton OL, Buckley RF, Manning LK, Scott MR, Properzi MJ, Peña-Gómez C, Jacobs HIL, Chhatwal JP, Johnson KA, Sperling RA, Schultz AP. (2020) Resting-state functional connectivity and amyloid burden influence longitudinal cortical thinning in the default mode network in preclinical Alzheimer's disease. Neuroimage Clinical, 28:102407 (IF 3.4)
Buckley RF, Scott MR, Jacobs HIL, Schultz AP, Properzi MJ, Amariglio RE, Hohman TJ, Maybluym DV, Rubinstein ZB, Manning L, Hanseeuw BJ, Mormino EC, Rentz DM, Johnson KA, Sperling RA (2020). Sex mediates relationships between regional tau pathology and cognitive decline . Annals of Neurology, 88(5), 921-932 (IF 8.1)
Gramespacher H, Richter N, Edwin Thanarajah S, Jacobs HIL, Dillen KNH, Nellessen N, von Reutern B, Dronse J, Kukolja J, Fink GR, Onur OA (2020). Aberrant frontostriatal connectivity in Alzheimer's disease with positive palmomental reflex. European Journal of Neurology, 27(12), 2405-2414 (IF 4.5)
Jacobs HIL*, Priovoulos N*, Poser BA, Pagen LHG, Ivanov D, Verhey FRJ, Uludag K. (2020). Dynamic behaviour of the locus coeruleus during arousal-related memory processing in a multi-modal 7T fMRI paradigm. eLife, e52059 (IF 6.4)
Scott MR, Hampton OL, Buckley RF, Chhatwal JP, Hanseeuw BJ, Jacobs HIL, Properzi MJ, Sanchez JS, Johnson KA, Sperling RA, Schultz AP (2020). Inferior temporal tau is associated with accelerated prospective cortical thinning in clinically normal older adults. Neuroimage. 220, 116991 (IF 4.7)
Riphagen JM, Schmiedek L, Gronenschild EHBM, Yassa MA, Priovoulos N, Sack AT, Verhey FRJ, Jacobs HIL (2020) Associations between pattern separation and hippocampal subfield structure and function vary along the lifespan: a 7T imaging study. Scientific Reports. 101(1), 7572. (IF 3.8)
Pagen LHG, van de Ven V, Gronenschild EHBM, Priovoulos N, Verhey FRJ, Jacobs HIL. (2020) Contributions of cerebra-cerebellar default mode connectivity patterns to memory performance in mild cognitive impairment. Journal of Alzheimer's Disease. 75(2), 633-647. (IF 3.4)
Jacobs HIL, Augustinack JC, Schultz AP, Hanseeuw BJ, Locascio J, Amarillo RE, Papp KV, Rentz DM, Sperling RA, Johnson KA. (2020) The presubiculum links incipient amyloid and tau pathology to memory function in older persons. Neurology. 94(18), e1916-e1928. (IF 8.4)
d'Oleire Uquillas F, Jacobs HIL, Schultz AP, Hanseeuw BJ, Buckley RF, Sepulcre J, Pascual-Leone A, Donovan NJ, Johnson KA, Sperling RA, Vannini P (2020). Functional and pathological correlates of judgments of learning in cognitively unimpaired older adults. Cerebral Cortex, 30(3), 1974-1983. (IF 2.9)
Biddle KD, Jacobs HIL, d'Oleire Uquillas F, Zide BS, Kirn DR, Properzi MR, Rentz DM, Johnson KA, Sperling RA, Donovan NJ.(2020) Associations of widowhood and Beta-Amyloid with cognitive decline in cognitively unimpaired older adults. JAMA Network Open, 3(2), e200121 (IF 10.5)
Riphagen JM, Ramakers IHGM, Freeze WM, Pagen LHG, Hanseeuw BJ, Verbeek MM, Verhey FRJ, Jacobs HIL (2020). Linking APOE-E4, blood-brain barrier dysfunction and inflammation to Alzheimer's pathology. Neurobiology of Aging, 85, 96-103 (IF 3.7)
Freeze WM, Jacobs HIL, de Jong JJ, Verheggen ICM, Gronenschild EHBM, Palm WM, Hoff EI, Wardlaw JM, Jansen JFA, Verhey FRJ, Backes WH (2020). White matter hyperintensities mediate the association between blood-brain barrier leakage and information processing speed. Neurobiology of Aging, 85, 113-122 (IF 3.7)
Song TA, Chowdhury SR, Yang F, Jacobs HIL, Sepulcre J, Wedeen VJ, Johnson KA, Dutta J (2020) A physics-informed geometric learning model for pathological tau spread in Alzheimer's disease. Med Image Comput Comput Assist Interv, 12267, 418-427.
Farrell ME, Jiang S, Schultz AP, Properzi MJ, Price JC, Becker JA, Jacobs HIL, Hanseeuw BJ, Rentz DM, Villemagne VL, Papp KV, Mormino EC, Betensky RA, Johnson KA, Sperling RA, Buckley RF (2020) Defining the lowest threshold for amyloid-PET to predict future cognitive decline and amyloid accumulation. Neurology, 96(4), e619-e631 (IF 8.4).
Priovoulos N*, van Boxel SCJ*, Jacobs HIL, Poser BA, Uludag K, Verhey FRJ, Ivanov D (2020) Unraveling the contributions to the neuromelanin-MRI contrast. Brain Structure and Function, 225(9), 2757-2274, (IF 2.7)
Freeze WM, van der Thiel M, de Bresser J, Klijn CJM, van Etten ES, Jansen JFA, van der Weerd L, Jacobs HIL, Backes WH, van Veluw SJ (2020) CSF Enhancement on post-contrast fluid-attenuated inversion recovery images: a systematic review. Neuroimage Clinical, 28: 102456 (IF 3.4)
Hampton OL, Buckley RF, Manning LK, Scott MR, Properzi MJ, Peña-Gómez C, Jacobs HIL, Chhatwal JP, Johnson KA, Sperling RA, Schultz AP. (2020) Resting-state functional connectivity and amyloid burden influence longitudinal cortical thinning in the default mode network in preclinical Alzheimer's disease. Neuroimage Clinical, 28:102407 (IF 3.4)
Buckley RF, Scott MR, Jacobs HIL, Schultz AP, Properzi MJ, Amariglio RE, Hohman TJ, Maybluym DV, Rubinstein ZB, Manning L, Hanseeuw BJ, Mormino EC, Rentz DM, Johnson KA, Sperling RA (2020). Sex mediates relationships between regional tau pathology and cognitive decline . Annals of Neurology, 88(5), 921-932 (IF 8.1)
Gramespacher H, Richter N, Edwin Thanarajah S, Jacobs HIL, Dillen KNH, Nellessen N, von Reutern B, Dronse J, Kukolja J, Fink GR, Onur OA (2020). Aberrant frontostriatal connectivity in Alzheimer's disease with positive palmomental reflex. European Journal of Neurology, 27(12), 2405-2414 (IF 4.5)
Jacobs HIL*, Priovoulos N*, Poser BA, Pagen LHG, Ivanov D, Verhey FRJ, Uludag K. (2020). Dynamic behaviour of the locus coeruleus during arousal-related memory processing in a multi-modal 7T fMRI paradigm. eLife, e52059 (IF 6.4)
Scott MR, Hampton OL, Buckley RF, Chhatwal JP, Hanseeuw BJ, Jacobs HIL, Properzi MJ, Sanchez JS, Johnson KA, Sperling RA, Schultz AP (2020). Inferior temporal tau is associated with accelerated prospective cortical thinning in clinically normal older adults. Neuroimage. 220, 116991 (IF 4.7)
Riphagen JM, Schmiedek L, Gronenschild EHBM, Yassa MA, Priovoulos N, Sack AT, Verhey FRJ, Jacobs HIL (2020) Associations between pattern separation and hippocampal subfield structure and function vary along the lifespan: a 7T imaging study. Scientific Reports. 101(1), 7572. (IF 3.8)
Pagen LHG, van de Ven V, Gronenschild EHBM, Priovoulos N, Verhey FRJ, Jacobs HIL. (2020) Contributions of cerebra-cerebellar default mode connectivity patterns to memory performance in mild cognitive impairment. Journal of Alzheimer's Disease. 75(2), 633-647. (IF 3.4)
Jacobs HIL, Augustinack JC, Schultz AP, Hanseeuw BJ, Locascio J, Amarillo RE, Papp KV, Rentz DM, Sperling RA, Johnson KA. (2020) The presubiculum links incipient amyloid and tau pathology to memory function in older persons. Neurology. 94(18), e1916-e1928. (IF 8.4)
d'Oleire Uquillas F, Jacobs HIL, Schultz AP, Hanseeuw BJ, Buckley RF, Sepulcre J, Pascual-Leone A, Donovan NJ, Johnson KA, Sperling RA, Vannini P (2020). Functional and pathological correlates of judgments of learning in cognitively unimpaired older adults. Cerebral Cortex, 30(3), 1974-1983. (IF 2.9)
Biddle KD, Jacobs HIL, d'Oleire Uquillas F, Zide BS, Kirn DR, Properzi MR, Rentz DM, Johnson KA, Sperling RA, Donovan NJ.(2020) Associations of widowhood and Beta-Amyloid with cognitive decline in cognitively unimpaired older adults. JAMA Network Open, 3(2), e200121 (IF 10.5)
Riphagen JM, Ramakers IHGM, Freeze WM, Pagen LHG, Hanseeuw BJ, Verbeek MM, Verhey FRJ, Jacobs HIL (2020). Linking APOE-E4, blood-brain barrier dysfunction and inflammation to Alzheimer's pathology. Neurobiology of Aging, 85, 96-103 (IF 3.7)
Freeze WM, Jacobs HIL, de Jong JJ, Verheggen ICM, Gronenschild EHBM, Palm WM, Hoff EI, Wardlaw JM, Jansen JFA, Verhey FRJ, Backes WH (2020). White matter hyperintensities mediate the association between blood-brain barrier leakage and information processing speed. Neurobiology of Aging, 85, 113-122 (IF 3.7)
2019
Vannini P, d'Oleire Uquillas F, Jacobs HIL, Sepulcre J, Gatchel J, Amarillo RE, Hanseeuw B, Papp KV, Hedden T, Rentz DM, Pascual-Leone A, Johnson KA, Sperling RA (2019). Decreased meta-memory is associated with is early tauopathy in cognitively unimpaired older individuals. Neuroimage Clinical, 24, 102097 (IF 3.4)
Duecker F, Mayrhofer HC, Jacobs HIL, Sack AT (2019). No effect of cold pressor test-induced arousal on attentional benefits and costs in an endogenous spatial orienting paradigm. Neuropsychologia, 135, 107250.(IF 2.0)
Jacobs HIL. Focus on the blue locus for learning. Nature Human Behaviour, 3(11), 1143-1144. (IF 22.3)
Richter N, Nellessen N, Dronse J, Dillen K, Jacobs HIL, Langen KJ, Dietlein M, Kracht L, Neumaier B, Fink GR, Kukolja J, Onur OA (2019). Spatial distributions of cholinergic impairment and neuronal hypo metabolism differ in MCI due to AD. Neuroimage Clinical, 24, 101978 (IF 3.4)
Priovoulos N, Poser BA, Ivanov D, Verhey FR, Jacobs HIL. (2019). In vivo imaging of the nucleus of the solitary tract with Magnetization Transfer at 7 Tesla. Neuroimage, 201, 116071 (IF 4.7)
Freeze WM, Ter Weele DN, Palm WM, van Hooren RW, Hoff EI, Jansen JFA, Jacobs HIL, Verhey FR, Backes WH. (2019) Optimal detection of subtle gadolinium leakage in CSF with heavily T2-weighted Fluid-Attenuated Inversion Recovery Imaging, American Journal of Neuroradiology, 40(9), 1481-1483 (IF 3.1)
Betts MJ, Kirilina E, Otaduy M, Ivanov D, Acosta-Cabronero J, Callaghan M Lambert C, Cardenas-Blanco A, Pine K, Passamonti L, Loane C, Keuken MC, Trujillo P, Lüsebrink F, Mattern H, Liu K, Priovoulos N, Fliessbach K, Dahl MJ, Maass A, Madelung CF, Meder D, Ehrenberg AJ, Speck O, Weiskopf N, Dolan R, Inglis B, Tosun D, Morawski M, Zucca FA, Siebner H, Mather M, Uludag K, Heinsen H, Poser BA, Howard R, Zecca L, Rowe JB, Grinberg LT, Jacobs HIL, Düzel E*, Hämmerer D* (2019). Locus coeruleus imaging as a biomarker for neurodegeneration. Brain, 142(9), 2558-2571 (IF 11.9).
Song TA, Roy Chowdhury S, Yang F, Jacobs HIL, El Fakhri G, Li Q, Johnson KA, Dutta J. (2019). Graph convolutional neural networks for Alzheimer's disease classification. Proc IEEE Int Symp Biomed Imag, 414-419.
Biddle KD, Uquillas FD, Jacobs HIL, Zide B, Kirn DR, Rente DM, Johnson KA, Sperling RA, Donovan NJ (2019). Social engagement and amyloid-beta related cognitive decline in cognitively normal older adults. American Journal of Geriatric Psychiatry, 27(11), 1247-1256 (IF 4.4)
Bischof GN, Jacobs HIL. (2019) Subthreshold amyloid and its biological and clinical meaning. Neurology. 93(2), 72-79 (IF 8.4)
Hanseeuw BJ, Betensky RA, Jacobs HIL, Schultz AP, Sepulcre J, Becker JA, Cosio DMO, Farrell M, Quiroz YT, Mormino EC, Buckley RF, Papp KV, Amariglio RA, Dewachter I, Ivanoiu A, Huijbers W, Hedder T, Marshall GA, Chhatwal JP, Rentz DM, Sperling RA, Johnson KA (2019). Association of amyloid and tau with cognition in preclinical Alzheimer disease: a longitudinal study. JAMA Neurology, 76(8), 915-924 (IF 20.9)
Yang F, Roy Chowdhury S, Jacobs HIL, Johnson KA, Dutta J (2019). A longitudinal model for tau aggregation in Alzheimer's disease based on structural connectivity. Inf Process Med Imaging, 11492, 384-393.
Buckley RF, Mormino EC, Chhatwal J, Schultz AP, Rabin JS, Rentz DM, Acar D, Properzi MJ, Dumurgier J, Jacobs HIL, Gomez-Isla T, Johnson KA, Sperling RA, Hanseeuw BJ (2019). Associations between baseline amyloid, sex and APOE on subsequent tau accumulation in cerebrospinal fluid. Neurobiology of Aging, 78, 178-185 (IF 3.7)
Fuller JT, Cronin-Golomb A, Gatchel JR, Norton DJ, Guzman-Velez E, Jacobs HIL, Hanseeuw B, Padilla-Delgado E, Artola A, Baena A, Bocanegra Y, Kosik KS, Chen K, Tariot PN, Johnson K, Sperling RA, Reiman EM, Lopera F, Quiroz YT (2019). Biological and cognitive markers of Presenilin1 E280A Autosomal Dominant Alzheimer's disease: a comprehensive review of the Colombian kindred. The Journal of Prevention of Alzheimer's disease, 6(2), 112-120..(IF 8.5)
Buckley RF, Mormino EC, Rabin JS, Hohman TJ, Landau S, Hanseeuw BJ, Jacobs HIL, Papp KV, Amariglio RE, Properzi MJ, Schultz AP, Kirn D, Scott MR, Hedden T, Farrell M, Price J, Chhatwal J, Rentz DM, Villemagne VL, Johnson KA, Sperling RA. (2019). Sex differences in the association between global amyloid and regional tau deposition measured by positron emission tomography in clinically normal older adults. JAMA Neurology, 76(5), 542-551 (IF 20.9)
Freeze WM, Bacskai BJ, Frosch MP, Jacobs HIL, Backes WH, Greenberg SM, van Veluw SJ. (2019). Blood-brain barrier leakage and microvascular lesions in Cerebral Amyloid Angiopathy. Stroke, 50(2),328-335 (IF 7.9)
Wolters A.F., van de Weijer S.C.F., Leentjens A.F.G., Duits A.A., Jacobs H.I.L., Kuijf M.L. (2019). Resting-state fMRI in Parkinson's disease patients with cognitive impairment: a meta-analysis. Parkinsonism & Related Disorders, 62, 16-27 (IF 3.1)
Mayrhofer HC, Duecker F, van de Ven V, Jacobs HIL, Sack AT (2019). Hemifield-specific correlations between cue-related blood oxygen level dependent activity in bilateral nodes of the dorsal attention network and attentional benefits in a spatial orienting paradigm. Journal of Cognitive Neuroscience. 21, 1-14 (IF 3.1)
Sperling R.A., Mormino E.C., Schultz A.P., Betensky R.A., Papp K.V., Amariglio R.E., Hanseeuw B.J., Buckley R., Chhatwal J, Hedden T., Marshall G.A., Quiroz Y.T., Donovan N.J., Jackson J., Gatchel J.R., Rabin J.S., Jacobs H., Yang H.S., Properzi M., Kirn D.R., Rentz D.M., Johnson K.A.. (2019). The impact of Aβ and tau on prospective cognitive decline in older individuals. Annals of Neurology, 85 (2), 181-193 (IF: 8.1)
Duecker F, Mayrhofer HC, Jacobs HIL, Sack AT (2019). No effect of cold pressor test-induced arousal on attentional benefits and costs in an endogenous spatial orienting paradigm. Neuropsychologia, 135, 107250.(IF 2.0)
Jacobs HIL. Focus on the blue locus for learning. Nature Human Behaviour, 3(11), 1143-1144. (IF 22.3)
Richter N, Nellessen N, Dronse J, Dillen K, Jacobs HIL, Langen KJ, Dietlein M, Kracht L, Neumaier B, Fink GR, Kukolja J, Onur OA (2019). Spatial distributions of cholinergic impairment and neuronal hypo metabolism differ in MCI due to AD. Neuroimage Clinical, 24, 101978 (IF 3.4)
Priovoulos N, Poser BA, Ivanov D, Verhey FR, Jacobs HIL. (2019). In vivo imaging of the nucleus of the solitary tract with Magnetization Transfer at 7 Tesla. Neuroimage, 201, 116071 (IF 4.7)
Freeze WM, Ter Weele DN, Palm WM, van Hooren RW, Hoff EI, Jansen JFA, Jacobs HIL, Verhey FR, Backes WH. (2019) Optimal detection of subtle gadolinium leakage in CSF with heavily T2-weighted Fluid-Attenuated Inversion Recovery Imaging, American Journal of Neuroradiology, 40(9), 1481-1483 (IF 3.1)
Betts MJ, Kirilina E, Otaduy M, Ivanov D, Acosta-Cabronero J, Callaghan M Lambert C, Cardenas-Blanco A, Pine K, Passamonti L, Loane C, Keuken MC, Trujillo P, Lüsebrink F, Mattern H, Liu K, Priovoulos N, Fliessbach K, Dahl MJ, Maass A, Madelung CF, Meder D, Ehrenberg AJ, Speck O, Weiskopf N, Dolan R, Inglis B, Tosun D, Morawski M, Zucca FA, Siebner H, Mather M, Uludag K, Heinsen H, Poser BA, Howard R, Zecca L, Rowe JB, Grinberg LT, Jacobs HIL, Düzel E*, Hämmerer D* (2019). Locus coeruleus imaging as a biomarker for neurodegeneration. Brain, 142(9), 2558-2571 (IF 11.9).
Song TA, Roy Chowdhury S, Yang F, Jacobs HIL, El Fakhri G, Li Q, Johnson KA, Dutta J. (2019). Graph convolutional neural networks for Alzheimer's disease classification. Proc IEEE Int Symp Biomed Imag, 414-419.
Biddle KD, Uquillas FD, Jacobs HIL, Zide B, Kirn DR, Rente DM, Johnson KA, Sperling RA, Donovan NJ (2019). Social engagement and amyloid-beta related cognitive decline in cognitively normal older adults. American Journal of Geriatric Psychiatry, 27(11), 1247-1256 (IF 4.4)
Bischof GN, Jacobs HIL. (2019) Subthreshold amyloid and its biological and clinical meaning. Neurology. 93(2), 72-79 (IF 8.4)
Hanseeuw BJ, Betensky RA, Jacobs HIL, Schultz AP, Sepulcre J, Becker JA, Cosio DMO, Farrell M, Quiroz YT, Mormino EC, Buckley RF, Papp KV, Amariglio RA, Dewachter I, Ivanoiu A, Huijbers W, Hedder T, Marshall GA, Chhatwal JP, Rentz DM, Sperling RA, Johnson KA (2019). Association of amyloid and tau with cognition in preclinical Alzheimer disease: a longitudinal study. JAMA Neurology, 76(8), 915-924 (IF 20.9)
Yang F, Roy Chowdhury S, Jacobs HIL, Johnson KA, Dutta J (2019). A longitudinal model for tau aggregation in Alzheimer's disease based on structural connectivity. Inf Process Med Imaging, 11492, 384-393.
Buckley RF, Mormino EC, Chhatwal J, Schultz AP, Rabin JS, Rentz DM, Acar D, Properzi MJ, Dumurgier J, Jacobs HIL, Gomez-Isla T, Johnson KA, Sperling RA, Hanseeuw BJ (2019). Associations between baseline amyloid, sex and APOE on subsequent tau accumulation in cerebrospinal fluid. Neurobiology of Aging, 78, 178-185 (IF 3.7)
Fuller JT, Cronin-Golomb A, Gatchel JR, Norton DJ, Guzman-Velez E, Jacobs HIL, Hanseeuw B, Padilla-Delgado E, Artola A, Baena A, Bocanegra Y, Kosik KS, Chen K, Tariot PN, Johnson K, Sperling RA, Reiman EM, Lopera F, Quiroz YT (2019). Biological and cognitive markers of Presenilin1 E280A Autosomal Dominant Alzheimer's disease: a comprehensive review of the Colombian kindred. The Journal of Prevention of Alzheimer's disease, 6(2), 112-120..(IF 8.5)
Buckley RF, Mormino EC, Rabin JS, Hohman TJ, Landau S, Hanseeuw BJ, Jacobs HIL, Papp KV, Amariglio RE, Properzi MJ, Schultz AP, Kirn D, Scott MR, Hedden T, Farrell M, Price J, Chhatwal J, Rentz DM, Villemagne VL, Johnson KA, Sperling RA. (2019). Sex differences in the association between global amyloid and regional tau deposition measured by positron emission tomography in clinically normal older adults. JAMA Neurology, 76(5), 542-551 (IF 20.9)
Freeze WM, Bacskai BJ, Frosch MP, Jacobs HIL, Backes WH, Greenberg SM, van Veluw SJ. (2019). Blood-brain barrier leakage and microvascular lesions in Cerebral Amyloid Angiopathy. Stroke, 50(2),328-335 (IF 7.9)
Wolters A.F., van de Weijer S.C.F., Leentjens A.F.G., Duits A.A., Jacobs H.I.L., Kuijf M.L. (2019). Resting-state fMRI in Parkinson's disease patients with cognitive impairment: a meta-analysis. Parkinsonism & Related Disorders, 62, 16-27 (IF 3.1)
Mayrhofer HC, Duecker F, van de Ven V, Jacobs HIL, Sack AT (2019). Hemifield-specific correlations between cue-related blood oxygen level dependent activity in bilateral nodes of the dorsal attention network and attentional benefits in a spatial orienting paradigm. Journal of Cognitive Neuroscience. 21, 1-14 (IF 3.1)
Sperling R.A., Mormino E.C., Schultz A.P., Betensky R.A., Papp K.V., Amariglio R.E., Hanseeuw B.J., Buckley R., Chhatwal J, Hedden T., Marshall G.A., Quiroz Y.T., Donovan N.J., Jackson J., Gatchel J.R., Rabin J.S., Jacobs H., Yang H.S., Properzi M., Kirn D.R., Rentz D.M., Johnson K.A.. (2019). The impact of Aβ and tau on prospective cognitive decline in older individuals. Annals of Neurology, 85 (2), 181-193 (IF: 8.1)
2018
d'Oleire Uquillas F., Jacobs H.I.L., Biddle K.D., Properzi M., Hanseeuw B., Schultz A.P., Rentz D.M., Johnson K.A., Sperling R.A., Donovan N.J. (2018). Regional tau pathology and loneliness in cognitively normal older adults. Translational Psychiatry, 8(1), 282 (IF: 5.8)
Freeze WM, Jacobs HIL, Schreuder FHBM, van Oostenbrugge RJ, Backes WH, Verhey FR, Klijn CJM (2018). Blood-Brain Barrier dysfunction in small vessel disease related intracerebral hemorrhage. Frontiers Neurology, 9, 926 (IF 2.7)
Jacobs H.I.L., Buckley R.F. (2018).. Where do white matter alterations dovetail with the cascade model of Alzheimer's disease? Brain. 141 (10), 2830-2833 (IF 11.9)
Sepulcre J, Grothe MH, d'Oleire Uquillas F, Ortiz-Terán L, Diez I, Yang HS, Jacobs HIL, Hanseeuw BJ, Li Q, El-Fakhri G, Sperling RA, Johnson KA. (2018). Neurogenetic contributions to amyloid beta and tau spreading in the human cortex. Nature Medicine, 24(12), 1910-1918 (IF 58.7).
Bachmann C, Jacobs HIL, Porta Mana P, Dillen K, Richter N, von Reutern B, Dronse J, Onur OA, Langen KJ, Fink GR, Kukolja J, Morrison A. (2018). On the extraction and analysis of graphs from resting-state fMRI to support a correct and robust diagnostic tool for Alzheimer's disease. Frontiers in Neuroscience, 12, 528 (IF 3.2).
Müller-Ehrenberg L, Riphagen JM, Verhey FRJ, Sack AT, Jacobs HIL (2018). Alzheimer's disease biomarkers have distinct associations with specific hippocampal subfield volumes. Journal Of Alzheimer's Disease, 66(2), 811-823 (IF 3.4)
Rienäcker F, Jacobs HIL, Van Heighten CM, Van Gerven PWM (2018). Practice makes perfect: high performance gains in older adults engaged in selective attention within and across sensory modalities. Acta Psychologica. 191, 101-111. (IF 2.1)
van Hooren RWE, Riphagen JM, Jacobs HIL (2018). Internetwork connectivity and amyloid-beta linked to cognitive decline in preclinical Alzheimer's disease: a longitudinal cohort study. Alzheimer's Research and Therapy, 10:88 (IF 8.0)
Rosenberg J, Jacobs HIL, Maximov II, Reske M, Shah J (2018). Chronotype differences in cortical thickness: grey matter reflects when you go to bed. Brain Structure and Function, 223(7), 3411-3421 (IF 2.7)
Buckley RF, Mormino EC, Amariglio RE, Properzi MJ, Rabin JS, Lim YY, Papp KV, Jacobs HIL, Burnham S, Hanseeuw BJ, Doré V, Dobson A, Masters CL, Waller M, Rowe CC, Maruff P, Donohue MC, Rente DM, Kirn D, Hedden T, Chhatwal JP, Schultz AP, Johnson KA, Villemagne VL, Sperling RA, on behalf of collaborators in the Alzheimer's Disease Neuroimaging Initiative, the Australian Imaging Biomarker and Lifespan Study of Aging, the Harvard Aging Brain Study. (2018) Sex, amyloid and APOE-E4 and risk of cognitive decline in preclinical Alzheimer's disease: Findings from three well-characterized cohorts. Alzheimer's & Dementia, 14(9), 1193-1203 (IF 13.1)
Jacobs HIL, Müller-Ehrenberg L, Priovoulos N, Roebroeck A. (2018) Curvilinear locus coeruleus functional connectivity trajectories over the adult lifespan: a 7T MRI study. Neurobiology of Aging, 69, 167-176 (IF 3.7)
Hanseeuw BJ, Betensky RA, Mormino EC, Schultz AP, Sepulcre J, Becker JA, Jacobs HIL, Buckley RF, LaPoint M, Vannini P, Donovan NJ, Chhatwal JP, Marshall GA, Papp KV, Amariglio RE, Rentz DM, Sperling RA, Johnson KA, for the Alzheimer's Disease Neuroimaging Initiative and the Harvard Aging Brain Study. (2018) PET staging of amyloidosis using striatum. Alzheimer's & Dementia, 14(10), 1281-1292 (IF 13.1)
Riphagen JM, Gronenschild EHBM, Salat DH, Freeze WM, Ivanov D, Clerx L, Verhey FRJ, Aalten P, Jacobs HIL (2018). Shades of white: diffusion properties of T1- and FLAIR defined white matter signal abnormalities differ in stages from cognitively normal to dementia. Neurobiology of Aging, 68, 48-58 (IF 3.7)
Lee CM*, Jacobs HIL*, Marquié M, Becker JA, Andrea NV, Jin DS, Schultz AP, Frosch MP, Gómez-Isla T, Sperling RA, Johnson KA (2018). 18F-Flortaucipir Binding in Choroid Plexus: Related to Race and Hippocampus signal. Journal Of Alzheimer's Disease, 62, 1691-1702 (IF 3.4)
Jacobs HIL, Hedden T, Schultz AP, Sepulcre J, Perea RD, Amariglio RE, Papp KV, Rentz DM, Sperling RA & Johnson KA (2018). Structural tract alterations predict down-stream tau accumulation in amyloid positive older individuals. Nature Neuroscience, 21(3), 424-431 (IF 21.3)
Jacobs H.I.L., Hopkins D.A., Mayrhofer H.C., Bruner E., van Leeuwen F.W., Raaijmakers W. & Schmahmann J.D. (2017). The cerebellum in Alzheimer's disease: evaluating its role in cognitive decline. Brain, 141(1), 37-47 (IF 11.9)
Priovoulos N., Jacobs H.I.L., Ivanov D., Uludag K., Verhey F.R.J. & Poser B.A. (2018). High-resolution in vivo imaging of human locus coeruleus by magnetization transfer MRI at 3T and 7T. Neuroimage, 168, 427-436 (IF 4.7)
Freeze WM, Jacobs HIL, Schreuder FHBM, van Oostenbrugge RJ, Backes WH, Verhey FR, Klijn CJM (2018). Blood-Brain Barrier dysfunction in small vessel disease related intracerebral hemorrhage. Frontiers Neurology, 9, 926 (IF 2.7)
Jacobs H.I.L., Buckley R.F. (2018).. Where do white matter alterations dovetail with the cascade model of Alzheimer's disease? Brain. 141 (10), 2830-2833 (IF 11.9)
Sepulcre J, Grothe MH, d'Oleire Uquillas F, Ortiz-Terán L, Diez I, Yang HS, Jacobs HIL, Hanseeuw BJ, Li Q, El-Fakhri G, Sperling RA, Johnson KA. (2018). Neurogenetic contributions to amyloid beta and tau spreading in the human cortex. Nature Medicine, 24(12), 1910-1918 (IF 58.7).
Bachmann C, Jacobs HIL, Porta Mana P, Dillen K, Richter N, von Reutern B, Dronse J, Onur OA, Langen KJ, Fink GR, Kukolja J, Morrison A. (2018). On the extraction and analysis of graphs from resting-state fMRI to support a correct and robust diagnostic tool for Alzheimer's disease. Frontiers in Neuroscience, 12, 528 (IF 3.2).
Müller-Ehrenberg L, Riphagen JM, Verhey FRJ, Sack AT, Jacobs HIL (2018). Alzheimer's disease biomarkers have distinct associations with specific hippocampal subfield volumes. Journal Of Alzheimer's Disease, 66(2), 811-823 (IF 3.4)
Rienäcker F, Jacobs HIL, Van Heighten CM, Van Gerven PWM (2018). Practice makes perfect: high performance gains in older adults engaged in selective attention within and across sensory modalities. Acta Psychologica. 191, 101-111. (IF 2.1)
van Hooren RWE, Riphagen JM, Jacobs HIL (2018). Internetwork connectivity and amyloid-beta linked to cognitive decline in preclinical Alzheimer's disease: a longitudinal cohort study. Alzheimer's Research and Therapy, 10:88 (IF 8.0)
Rosenberg J, Jacobs HIL, Maximov II, Reske M, Shah J (2018). Chronotype differences in cortical thickness: grey matter reflects when you go to bed. Brain Structure and Function, 223(7), 3411-3421 (IF 2.7)
Buckley RF, Mormino EC, Amariglio RE, Properzi MJ, Rabin JS, Lim YY, Papp KV, Jacobs HIL, Burnham S, Hanseeuw BJ, Doré V, Dobson A, Masters CL, Waller M, Rowe CC, Maruff P, Donohue MC, Rente DM, Kirn D, Hedden T, Chhatwal JP, Schultz AP, Johnson KA, Villemagne VL, Sperling RA, on behalf of collaborators in the Alzheimer's Disease Neuroimaging Initiative, the Australian Imaging Biomarker and Lifespan Study of Aging, the Harvard Aging Brain Study. (2018) Sex, amyloid and APOE-E4 and risk of cognitive decline in preclinical Alzheimer's disease: Findings from three well-characterized cohorts. Alzheimer's & Dementia, 14(9), 1193-1203 (IF 13.1)
Jacobs HIL, Müller-Ehrenberg L, Priovoulos N, Roebroeck A. (2018) Curvilinear locus coeruleus functional connectivity trajectories over the adult lifespan: a 7T MRI study. Neurobiology of Aging, 69, 167-176 (IF 3.7)
Hanseeuw BJ, Betensky RA, Mormino EC, Schultz AP, Sepulcre J, Becker JA, Jacobs HIL, Buckley RF, LaPoint M, Vannini P, Donovan NJ, Chhatwal JP, Marshall GA, Papp KV, Amariglio RE, Rentz DM, Sperling RA, Johnson KA, for the Alzheimer's Disease Neuroimaging Initiative and the Harvard Aging Brain Study. (2018) PET staging of amyloidosis using striatum. Alzheimer's & Dementia, 14(10), 1281-1292 (IF 13.1)
Riphagen JM, Gronenschild EHBM, Salat DH, Freeze WM, Ivanov D, Clerx L, Verhey FRJ, Aalten P, Jacobs HIL (2018). Shades of white: diffusion properties of T1- and FLAIR defined white matter signal abnormalities differ in stages from cognitively normal to dementia. Neurobiology of Aging, 68, 48-58 (IF 3.7)
Lee CM*, Jacobs HIL*, Marquié M, Becker JA, Andrea NV, Jin DS, Schultz AP, Frosch MP, Gómez-Isla T, Sperling RA, Johnson KA (2018). 18F-Flortaucipir Binding in Choroid Plexus: Related to Race and Hippocampus signal. Journal Of Alzheimer's Disease, 62, 1691-1702 (IF 3.4)
Jacobs HIL, Hedden T, Schultz AP, Sepulcre J, Perea RD, Amariglio RE, Papp KV, Rentz DM, Sperling RA & Johnson KA (2018). Structural tract alterations predict down-stream tau accumulation in amyloid positive older individuals. Nature Neuroscience, 21(3), 424-431 (IF 21.3)
Jacobs H.I.L., Hopkins D.A., Mayrhofer H.C., Bruner E., van Leeuwen F.W., Raaijmakers W. & Schmahmann J.D. (2017). The cerebellum in Alzheimer's disease: evaluating its role in cognitive decline. Brain, 141(1), 37-47 (IF 11.9)
Priovoulos N., Jacobs H.I.L., Ivanov D., Uludag K., Verhey F.R.J. & Poser B.A. (2018). High-resolution in vivo imaging of human locus coeruleus by magnetization transfer MRI at 3T and 7T. Neuroimage, 168, 427-436 (IF 4.7)
2017
Bos I., Verhey F.R., Ramakers I.H.G.B., Jacobs H.I.L., Soininen H., Freund-Levi Y., Hampel H., Tsolaki M., Wallin A.K., van Buchem M.A., Oleksik A., Verbeek M.M., Olde Rikkert M., van der Flier W.M., Scheltens F., Aalten P., Visser P.J. & Vos S.J.B. (2017). Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline. Alzheimer's Research & Therapy, 9(1), 101, (IF 8.0)
Uquillas F.O., Jacobs H.I.L., Hanseeuw B.,Marshall G.A., Properz M., Schultz A.P., LaPoint M.R., Johnson K.A., Sperling R.A. & Vannini P. (2017). Interactive versus additive relationships between regional cortical thinning and amyloid burden in predicting clinical decline in mild AD and MCI individuals. Neuroimage Clinical, 17,388-396 (IF 3.4)
Freeze W.M., Schnerr R.S., Palm W.M., Jansen J.F., Jacobs H.I.L., Hoff E.I., Verhey F.R.J., & Backes W.H. (2017). Pericortical enhancement on delayed postgadolinium fluid-attenuated inversion recovery images in normal aging, mild cognitive impairment, and Alzheimer's disease. American Journal of Neuroradiology, 38(9),1742-1747 (IF 3.1)
Dillen K.N.H., Jacobs H.I.L., Kukolja J., Richter N., von Reutern B., Onur Ö.A., Langen K.-J. & Fink G.R.(2017) Functional disintegration of the default mode network in prodromal Alzheimer's disease. Journal Of Alzheimer's Disease, 59(1), 169-187 (IF 3.4)
Dekhtyar M., Papp K.V., Buckley R., Jacobs H.I.L., Schultz A.P., Johnson K.A., Sperling R.A. & Rentz D.M. (2017) Neuroimaging markers associated with maintenance of optimal memory performance in late-life. Neuropsychologia, 100, 164-170 (IF 2.0)
Cleutjens F.A.H.M., Ponds R.W.H.M., Spruit M.A.,, Burgmans S., Jacobs H.I.L., Gronenschild E.H.B.M., Staals J., Franssen F.M.E., Dijkstra J.B., Vanfleteren L.E.G.W., Hofman P.A., Wouters E.F.M. & Janssen D.J..A. (2017) The relationship between cerebral small vessel disease, hippocampal volume and cognitive functioning in patients with COPD: a MRI study. Frontiers in Aging Neuroscience, 30, 9-88 (IF 4.1)
Freeze W.M., Jacobs H.I.L., Gronenschild E.H.B.M., Jansen J.F.A., Burgmans S., Aalten P., Clerx L., Vos S.J., van Buchem M.A., Barkhof F., van der Flier W.M., Verbeek M.M., Olde Rikkert M., Backes W.H. & Verhey F.R.J. (2017) White matter hyperintensities potentiate hippocampal volume reduction in non-demented older individuals with abnormal amyloid-β. Journal of Alzheimer's Disease,, 55(1), 333-342 (IF 3.4)
Uquillas F.O., Jacobs H.I.L., Hanseeuw B.,Marshall G.A., Properz M., Schultz A.P., LaPoint M.R., Johnson K.A., Sperling R.A. & Vannini P. (2017). Interactive versus additive relationships between regional cortical thinning and amyloid burden in predicting clinical decline in mild AD and MCI individuals. Neuroimage Clinical, 17,388-396 (IF 3.4)
Freeze W.M., Schnerr R.S., Palm W.M., Jansen J.F., Jacobs H.I.L., Hoff E.I., Verhey F.R.J., & Backes W.H. (2017). Pericortical enhancement on delayed postgadolinium fluid-attenuated inversion recovery images in normal aging, mild cognitive impairment, and Alzheimer's disease. American Journal of Neuroradiology, 38(9),1742-1747 (IF 3.1)
Dillen K.N.H., Jacobs H.I.L., Kukolja J., Richter N., von Reutern B., Onur Ö.A., Langen K.-J. & Fink G.R.(2017) Functional disintegration of the default mode network in prodromal Alzheimer's disease. Journal Of Alzheimer's Disease, 59(1), 169-187 (IF 3.4)
Dekhtyar M., Papp K.V., Buckley R., Jacobs H.I.L., Schultz A.P., Johnson K.A., Sperling R.A. & Rentz D.M. (2017) Neuroimaging markers associated with maintenance of optimal memory performance in late-life. Neuropsychologia, 100, 164-170 (IF 2.0)
Cleutjens F.A.H.M., Ponds R.W.H.M., Spruit M.A.,, Burgmans S., Jacobs H.I.L., Gronenschild E.H.B.M., Staals J., Franssen F.M.E., Dijkstra J.B., Vanfleteren L.E.G.W., Hofman P.A., Wouters E.F.M. & Janssen D.J..A. (2017) The relationship between cerebral small vessel disease, hippocampal volume and cognitive functioning in patients with COPD: a MRI study. Frontiers in Aging Neuroscience, 30, 9-88 (IF 4.1)
Freeze W.M., Jacobs H.I.L., Gronenschild E.H.B.M., Jansen J.F.A., Burgmans S., Aalten P., Clerx L., Vos S.J., van Buchem M.A., Barkhof F., van der Flier W.M., Verbeek M.M., Olde Rikkert M., Backes W.H. & Verhey F.R.J. (2017) White matter hyperintensities potentiate hippocampal volume reduction in non-demented older individuals with abnormal amyloid-β. Journal of Alzheimer's Disease,, 55(1), 333-342 (IF 3.4)
2016
Dillen K.N.H., Jacobs H.I.L., Kukolja J., von Reutern B., Richter N., Onur Ö.A., Dronse J., Langen K.-J. & Fink G.R.(2016) Aberrant functional connectivity differentiates retrosplenial cortex from posterior cingulate cortex in prodromal Alzheimer’s disease. Neurobiology of Aging, 44, 114-26 (IF 3.7)
2015
Clerx, L., Gronenschild, E.H.B.M., Echavarri, C., Verhey, F.R.J., Aalten, P. & Jacobs, H.I.L. (2015) Can FreeSurfer compete with manual volumetric measurements in Alzheimer’s disease? Current Alzheimer Research, 12(4), 358-67 (IF 1.8)
Jacobs, H.I.L., Riphagen, J.M., Razat, C.M., Wiese, S. & Sack, A.T. (2015) Transcutaneous vagus nerve stimulation boosts associative memory in older individuals. Neurobiology of Aging, 36(6), 1860-7 (IF 3.7)
Jacobs, H.I.L., Dillen, K.N., Risius, O., Göreci, Y., Onur, O.A., Fink, G.R. & Kukolja, J. (2015) Consolidation in older adults depends upon competition between resting-state networks. Frontiers in Aging Neuroscience, 6, 344 (IF 4.1)
Jacobs, H.I.L., Wiese, S., van de Ven, V., Gronenschild, E.H.B.M., Verhey, F.R.J. & Matthews, P.M. (2015) Relevance of parahippocampal - locus coeruleus connectivity to memory in early dementia. Neurobiology of Aging, 36(2), 618-26 (IF 3.7)
Jacobs, H.I.L., Gronenschild, E.H.B.M., Evers, E.A.T., Ramakers, I.H.G.B., Hofman, P.A.M., Backes, W.H., Jolles, J., Verhey, F.R.J. & van Boxtel, M.P.J. (2012) Visuospatial processing in early Alzheimer’s disease: a multimodal neuroimaging study. Cortex, 64, 394-406 (IF 3.3)
Jacobs, H.I.L., Riphagen, J.M., Razat, C.M., Wiese, S. & Sack, A.T. (2015) Transcutaneous vagus nerve stimulation boosts associative memory in older individuals. Neurobiology of Aging, 36(6), 1860-7 (IF 3.7)
Jacobs, H.I.L., Dillen, K.N., Risius, O., Göreci, Y., Onur, O.A., Fink, G.R. & Kukolja, J. (2015) Consolidation in older adults depends upon competition between resting-state networks. Frontiers in Aging Neuroscience, 6, 344 (IF 4.1)
Jacobs, H.I.L., Wiese, S., van de Ven, V., Gronenschild, E.H.B.M., Verhey, F.R.J. & Matthews, P.M. (2015) Relevance of parahippocampal - locus coeruleus connectivity to memory in early dementia. Neurobiology of Aging, 36(2), 618-26 (IF 3.7)
Jacobs, H.I.L., Gronenschild, E.H.B.M., Evers, E.A.T., Ramakers, I.H.G.B., Hofman, P.A.M., Backes, W.H., Jolles, J., Verhey, F.R.J. & van Boxtel, M.P.J. (2012) Visuospatial processing in early Alzheimer’s disease: a multimodal neuroimaging study. Cortex, 64, 394-406 (IF 3.3)
2014
Lückmann H., Jacobs, H.I.L. & Sack, A.T. (2014) The cross-functional role of frontoparietal regions in cognition - Internal attention as the overarching mechanism. Progress in Neurobiology, 116, 66-86 (IF 6.7)
Bruner, E., Rangel de Låzaro, G., de la Cuétara, J.M., Martin-Loeches, M., Colom, R. & Jacobs, H.I.L. (2014) Midsaggital brain variation and MRI shape analysis of the precuneus in adult individuals. Journal of Anatomy,224(4), 367-76 (IF 1.8)
Jacobs, H.I.L., Clerx, L., Gronenschild, E.H.B.M., Aalten, P. & Verhey, F.R.J. (2014) White matter hyperintensities are positively associated with cortical thickness in Alzheimer’s disease. Journal of Alzheimer’s Disease, 39(2), 409-22 (IF 3.4).
Bruner, E., Rangel de Låzaro, G., de la Cuétara, J.M., Martin-Loeches, M., Colom, R. & Jacobs, H.I.L. (2014) Midsaggital brain variation and MRI shape analysis of the precuneus in adult individuals. Journal of Anatomy,224(4), 367-76 (IF 1.8)
Jacobs, H.I.L., Clerx, L., Gronenschild, E.H.B.M., Aalten, P. & Verhey, F.R.J. (2014) White matter hyperintensities are positively associated with cortical thickness in Alzheimer’s disease. Journal of Alzheimer’s Disease, 39(2), 409-22 (IF 3.4).
2013
Clerx, L., Jacobs, H.I.L., Burgmans S., Gronenschild E.H.B.M., Uylings, H.B.M., Echávarri, C., Visser, P.J., Verhey, F.R.J. & Aalten, P. (2013) Sensitivity of different MRI-techniques to assess gray matter atrophy patterns in Alzheimer’s disease is region-specific. Current Alzheimer Research, 10(9), 940-951 (IF 1.8)
Jacobs, H.I.L., Radua, J., Lückmann, H. & Sack, A. (2013) Meta-analysis of functional network alterations in Alzheimer’s disease: towards a network biomarker. Neuroscience and Biobehavioral Reviews, 37(5), 753-765 (IF 7.6)
Bruner E*. & Jacobs, H.I.L.* (2013) Alzheimer’s disease: the downside of a highly evolved parietal lobe? Journal of Alzheimer’s Disease, 35(2), 227-240 (IF 3.4)
Mills, J.M., Nalpathamkalam, T., Jacobs, H.I.L., Janitz, C., Merico, D., Hu, P. & Janitz, M. (2013) RNA-Seq analysis of the parietal cortex in Alzheimer’s disease reveals alternatively spliced isoforms related to lipid metabolism. Neuroscience Letters, 536, 90-95 (IF 2.5)
Jacobs, H.I.L., Leritz, E.C., Williams, V.J., Van Boxtel, M.P.J. van der Elst, W., Jolles, J. & Verhey, F.R.J., McGlinchey, R.E., Milberg, W.P., & Salat, D.H. (2013). Association between white matter microstructure and cognition in older adults : the impact of vascular health. Human Brain Mapping, 34(1), 77-95 (IF 3.5)
Jacobs, H.I.L., Van Boxtel, M.P.J., Gronenschild, E.H.B.M., Uylings, H.B.M., Jolles, J. & Verhey, F.R.J. (2013) Decreased gray matter diffusivity: a potential early Alzheimer disease biomarker? Alzheimer’s & Dementia, 9(1), 93-97 (IF 13.1)
Jacobs, H.I.L., Radua, J., Lückmann, H. & Sack, A. (2013) Meta-analysis of functional network alterations in Alzheimer’s disease: towards a network biomarker. Neuroscience and Biobehavioral Reviews, 37(5), 753-765 (IF 7.6)
Bruner E*. & Jacobs, H.I.L.* (2013) Alzheimer’s disease: the downside of a highly evolved parietal lobe? Journal of Alzheimer’s Disease, 35(2), 227-240 (IF 3.4)
Mills, J.M., Nalpathamkalam, T., Jacobs, H.I.L., Janitz, C., Merico, D., Hu, P. & Janitz, M. (2013) RNA-Seq analysis of the parietal cortex in Alzheimer’s disease reveals alternatively spliced isoforms related to lipid metabolism. Neuroscience Letters, 536, 90-95 (IF 2.5)
Jacobs, H.I.L., Leritz, E.C., Williams, V.J., Van Boxtel, M.P.J. van der Elst, W., Jolles, J. & Verhey, F.R.J., McGlinchey, R.E., Milberg, W.P., & Salat, D.H. (2013). Association between white matter microstructure and cognition in older adults : the impact of vascular health. Human Brain Mapping, 34(1), 77-95 (IF 3.5)
Jacobs, H.I.L., Van Boxtel, M.P.J., Gronenschild, E.H.B.M., Uylings, H.B.M., Jolles, J. & Verhey, F.R.J. (2013) Decreased gray matter diffusivity: a potential early Alzheimer disease biomarker? Alzheimer’s & Dementia, 9(1), 93-97 (IF 13.1)
2012
Jacobs, H.I.L., Van Boxtel, M.P.J., Heinecke, A., Gronenschild, E.H.B.M., Backes, W.H., Jolles, J. & Verhey, F.R.J. (2012) Functional integration of parietal lobe activity in early Alzheimer's disease. Neurology, 78, 352-360 (IF 8.4)
Gronenschild, E.H.B.M., Habets, P., Jacobs, H.I.L., Mengelers,R., Rozendaal, N., van Os, J. & Marcelis, M. (2012) The effects of FreeSurfer version, workstation type, and Macintosh operating system version on neuroanatomical volume and cortical thickness measurements. PLoS ONE, 7(6), e38234 (IF 2.9)
Jacobs, H.I.L., van Boxtel, M.P.J., Gronenschild E.H.B.M., Williams V.J., Uylings, H.B.M., Burgmans, S., Jolles, J. & Verhey, F.R.J. (2012) Patterns of grey and white matter changes in individuals at risk for Alzheimer’s disease. Current Alzheimer Research, 9(9), 1097-1105 (IF 1.8)
Jacobs, H.I.L., van Boxtel, M.P.J., Jolles, J., Verhey, F.R. & Uylings, H.B.M. (2012). Parietal cortex matters in early Alzheimer’s Disease: an overview of structural, functional and metabolic findings. Neuroscience and Biobehavioral Reviews, 36(1), 297-309 (IF 7.6)
Jacobs, H.I.L., Visser, P.J., van Boxtel, M.P.J., Jolles, J. & Verhey, F.R.J. and members of the Descripa study. (2012). The association between white matter hyperintensities and executive decline in mild cognitive impairment is network dependent. Neurobiology of Aging, 33(1), 201.e201-208 (IF 3.7)
Gronenschild, E.H.B.M., Habets, P., Jacobs, H.I.L., Mengelers,R., Rozendaal, N., van Os, J. & Marcelis, M. (2012) The effects of FreeSurfer version, workstation type, and Macintosh operating system version on neuroanatomical volume and cortical thickness measurements. PLoS ONE, 7(6), e38234 (IF 2.9)
Jacobs, H.I.L., van Boxtel, M.P.J., Gronenschild E.H.B.M., Williams V.J., Uylings, H.B.M., Burgmans, S., Jolles, J. & Verhey, F.R.J. (2012) Patterns of grey and white matter changes in individuals at risk for Alzheimer’s disease. Current Alzheimer Research, 9(9), 1097-1105 (IF 1.8)
Jacobs, H.I.L., van Boxtel, M.P.J., Jolles, J., Verhey, F.R. & Uylings, H.B.M. (2012). Parietal cortex matters in early Alzheimer’s Disease: an overview of structural, functional and metabolic findings. Neuroscience and Biobehavioral Reviews, 36(1), 297-309 (IF 7.6)
Jacobs, H.I.L., Visser, P.J., van Boxtel, M.P.J., Jolles, J. & Verhey, F.R.J. and members of the Descripa study. (2012). The association between white matter hyperintensities and executive decline in mild cognitive impairment is network dependent. Neurobiology of Aging, 33(1), 201.e201-208 (IF 3.7)
2011
Jacobs, H.I.L., van Boxtel, M.P.J., Uylings, H.B.M., Gronenschild, E.H.B.M., Verhey, F.R.J., & Jolles, J. (2011) Atrophy of the parietal lobe in preclinical dementia. Brain and Cognition,75(2), 154-163 (IF 2.2)
Jacobs, H.I.L.,Van Boxtel, M.P.J. van der Elst, W.,Burgmans, S., Smeets, F., Gronenschild, E.H.B.M., Verhey, F.R., Uyling, H.B.M. & Jolles J.(2011). Increasing the diagnostic accuracy of the medial temporal lobe atrophy in Alzheimer’s Disease. Journal of Alzheimer’s Disease, 25, 477-490 (IF 3.4)
Echávarri, C., Aalten, P., Uylings, H.B.M., Jacobs, H.I.L., Visser, P.J., Gronenschild, E.H.B.M., Verhey, F.R.J., & Burgmans, S. (2011) Atrophy in the parahippocampal gyrus as an early biomarker of Alzheimer’s disease. Brain Structure and Function, 215(3-4), 265-71 (IF 2.7)
Burgmans, S., van Boxtel, M.P.J., van den Berg, K.E.M., Gronenschild, E.H.B.M, Jacobs, H.I.L., Jolles, J., & Uylings, H.B.M. (2011). The posterior parahippocampal gyrus is preferentially affected in age-related memory decline. Neurobiology of Aging, 32(9), 1572-1578 (IF 3.7)
Jacobs, H.I.L.,Van Boxtel, M.P.J. van der Elst, W.,Burgmans, S., Smeets, F., Gronenschild, E.H.B.M., Verhey, F.R., Uyling, H.B.M. & Jolles J.(2011). Increasing the diagnostic accuracy of the medial temporal lobe atrophy in Alzheimer’s Disease. Journal of Alzheimer’s Disease, 25, 477-490 (IF 3.4)
Echávarri, C., Aalten, P., Uylings, H.B.M., Jacobs, H.I.L., Visser, P.J., Gronenschild, E.H.B.M., Verhey, F.R.J., & Burgmans, S. (2011) Atrophy in the parahippocampal gyrus as an early biomarker of Alzheimer’s disease. Brain Structure and Function, 215(3-4), 265-71 (IF 2.7)
Burgmans, S., van Boxtel, M.P.J., van den Berg, K.E.M., Gronenschild, E.H.B.M, Jacobs, H.I.L., Jolles, J., & Uylings, H.B.M. (2011). The posterior parahippocampal gyrus is preferentially affected in age-related memory decline. Neurobiology of Aging, 32(9), 1572-1578 (IF 3.7)
Median Impact factor for our field (Clarivate journal citation reports 2023):
• Neurosciences 2.8
• Psychology 2.0
• Neuroimaging 2.4
• Clinical Neurology 2.4
Average impact factor of the publications (Clarivate journal citation reports 2023):
• First-author publications: 7.37
• All publications: 6.92
(Total impact factor: 948.50)
Google Scholar Citations Metrics
• Neurosciences 2.8
• Psychology 2.0
• Neuroimaging 2.4
• Clinical Neurology 2.4
Average impact factor of the publications (Clarivate journal citation reports 2023):
• First-author publications: 7.37
• All publications: 6.92
(Total impact factor: 948.50)
Google Scholar Citations Metrics
Books & Chapters in books
Bruner E & Jacobs HIL (2022). Alzheimer's disease, the parietal lobes and the evolution of the human genus. In: Evolutionary roots of human brain diseases. Edited by: Diederich NJ, Brüne M, Amun's K and Goetz CG. Oxford University Press
Jacobs H.I.L. (2011) Parietal matters in early Alzheimer's disease: evidence from structural and functional MRI. Maastricht: Maastricht University (dissertation).
National publications
Jacobs HIL (2020). De rol van noradrenaline bij de ziekte van Alzheimer. Tijdschrift voor psychiatrie, 62, 80-81 [Dutch]
Jacobs, H.I.L. (2013). Functional integration of parietal lobe activity in early Alzheimer’s disease: findings and implications. Klinische Neurophysiologie,44(1), 28-32 [German]
Jacobs, H.I.L. (2011). De rol van de parietaalkwab in de vroege fase van de ziekte van Alzheimer. Neuropraxis, 15(4), 113-120 [Dutch]